L González Selected Research

Haemophilus influenzae type b-polysaccharide vaccine-diphtheria toxoid conjugate

1/2015	Influence of breed and genotype on the onset and distribution of infectivity and disease-associated prion protein in sheep following oral infection with the bovine spongiform encephalopathy agent.
1/2014	Influence of polymorphisms in the prion protein gene on the pathogenesis and neuropathological phenotype of sheep scrapie after oral infection.
1/2014	Identical pathogenesis and neuropathological phenotype of scrapie in valine, arginine, glutamine/valine, arginine, glutamine sheep infected experimentally by the oral and conjunctival routes.
4/2013	Pathogenesis of scrapie in ARQ/ARQ sheep after subcutaneous infection: effect of lymphadenectomy and immune cell subset changes in relation to prion protein accumulation.
8/2012	Minimal involvement of the circumventricular organs in the pathogenesis of spontaneously arising and experimentally induced classical bovine spongiform encephalopathy.
8/2011	Neuropathological changes correlate temporally but not spatially with selected neuromodulatory responses in natural scrapie.
6/2009	Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent.
6/2009	Neuroinvasion in sheep transmissible spongiform encephalopathies: the role of the haematogenous route.
3/2009	Frequency and distribution of nerves in scrapie-affected and unaffected Peyer's patches and lymph nodes.
3/2008	Diagnosis of preclinical scrapie in live sheep by the immunohistochemical examination of rectal biopsies.

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L González Research Topics

Disease

20	Scrapie 04/2017 - 11/2001
18	Infections 10/2015 - 11/2001
10	Prion Diseases (Transmissible Spongiform Encephalopathies) 04/2017 - 04/2003
9	Neoplasms (Cancer) 01/2013 - 03/2000
8	Bovine Spongiform Encephalopathy (Mad Cow Disease) 01/2015 - 01/2004
5	Breast Neoplasms (Breast Cancer) 01/2012 - 03/2000
2	Insulin Resistance 10/2014 - 10/2011
2	Obesity 10/2014 - 03/2000
2	Hydrocephalus (Hydrocephaly) 01/2014 - 01/2014
2	Chronic Disease (Chronic Diseases) 10/2011 - 07/2010
2	Gliosis 08/2011 - 08/2007
2	Carcinoma (Carcinomatosis) 02/2008 - 03/2000
1	Patent Ductus Arteriosus 10/2015
1	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 10/2015
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 10/2015
1	Chorioamnionitis 10/2015
1	Necrotizing Enterocolitis 10/2015
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 05/2015
1	Amyloid Plaque 04/2014
1	Intra-Abdominal Hypertension 10/2012
1	Cerebral Palsy (Spastic Diplegia) 08/2012
1	Nervous System Diseases (Neurological Disorders) 07/2012
1	Hyperinsulinism (Hyperinsulinemia) 10/2011
1	Microsatellite Instability 06/2011
1	Adrenocortical Carcinoma 06/2011
1	Noninfiltrating Intraductal Carcinoma (DCIS) 09/2010
1	Folic Acid Deficiency (Folic Acid Deficiencies) 07/2010
1	Hypothyroidism 07/2010
1	Necrosis 02/2010
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2010
1	Neoplasm Metastasis (Metastasis) 07/2009
1	Renal Cell Carcinoma (Grawitz Tumor) 02/2008
1	Hiatal Hernia 09/2007
1	Chronic Renal Insufficiency 06/2007
1	Inflammation (Inflammations) 06/2007

Drug/Important Bio-Agent (IBA)

24	Prion ProteinsIBA 04/2017 - 11/2001
16	Haemophilus influenzae type b-polysaccharide vaccine-diphtheria toxoid conjugateIBA 01/2015 - 01/2002
4	AntibodiesIBA 07/2009 - 06/2005
3	Biological ProductsIBA 04/2017 - 10/2014
3	Codon (Codons)IBA 01/2015 - 07/2002
3	Pharmaceutical PreparationsIBA 01/2012 - 03/2000
3	Proteins (Proteins, Gene)FDA Link 06/2011 - 03/2000
3	PrPSc ProteinsIBA 05/2006 - 01/2004
3	Peptides (Polypeptides)IBA 01/2006 - 11/2001
2	Glutamine (L-Glutamine)FDA Link 01/2015 - 01/2014
2	Methionine (L-Methionine)FDA Link 01/2015 - 04/2013
2	Arginine (L-Arginine)FDA Link 01/2015 - 01/2014
2	Threonine (L-Threonine)FDA Link 01/2015 - 04/2013
2	Triglycerides (Triacylglycerol)IBA 10/2014 - 09/2000
2	Estrogen ReceptorsIBA 01/2012 - 03/2009
2	Metalloproteases (Metalloproteinases)IBA 09/2010 - 07/2009
2	Matrix Metalloproteinases (MMPs)IBA 09/2010 - 07/2009
2	IronIBA 02/2008 - 12/2003
2	DNA (Deoxyribonucleic Acid)IBA 01/2004 - 12/2003
2	Amino Acids FDA Link 04/2003 - 11/2001
1	ClathrinIBA 04/2017
1	Amyloid (Amyloid Fibrils)IBA 04/2017
1	CIGB-300IBA 05/2015
1	Alanine (L-Alanine)FDA Link 01/2015
1	Glucose (Dextrose)FDA LinkGeneric 10/2014
1	Valine (L-Valine)FDA Link 01/2014
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2013
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2012
1	Insulin (Novolin)FDA Link 10/2011
1	ParvalbuminsIBA 08/2011
1	Purinergic P1 Receptors (Adenosine Receptor)IBA 08/2011
1	SynaptophysinIBA 08/2011
1	Tissue Inhibitor of Metalloproteinase-3IBA 09/2010
1	Matrix Metalloproteinase 13IBA 09/2010
1	collagenase 1IBA 09/2010
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 09/2010
1	Tissue Inhibitor of Metalloproteinase-1IBA 09/2010
1	Biomarkers (Surrogate Marker)IBA 09/2010
1	Transaminases (Aminotransferases)IBA 07/2010
1	VitaminsIBA 07/2010
1	Glutens (Glutelin)IBA 07/2010
1	Propidium (Propidium Iodide)IBA 02/2010
1	Trypan Blue FDA Link 02/2010
1	seminaphthorhodaminefluorideIBA 02/2010
1	Annexin A5IBA 02/2010
1	LigandsIBA 03/2009
1	ProlactinIBA 03/2009
1	Estrogen Receptor alphaIBA 03/2009
1	Estrogens (Estrogen)FDA Link 03/2009
1	Hormones (Hormone)IBA 03/2009
1	PrionsIBA 03/2009
1	cytidylyl-(3'-5')-cytidine (CpC)IBA 02/2008
1	Monoclonal AntibodiesIBA 11/2007
1	AlbuminsIBA 06/2007

Therapy/Procedure

4	Therapeutics 08/2005 - 09/2000
1	Tocolysis 10/2015
1	Oral Administration 01/2014
1	Ventriculostomy 01/2014
1	Ventriculoperitoneal Shunt 01/2014
1	Neurosurgical Procedures 01/2014
1	Lymph Node Excision (Lymph Node Dissection) 04/2013
1	Decompression 10/2012
1	Blood Transfusion (Blood Transfusions) 01/2010
1	Transplantation 09/2007
1	Renal Dialysis (Hemodialysis) 06/2007